About Ofloxacin


Ofloxacin, or Floxin, is a prescription medication used to treat bacterial infections in the body. According to Drugs.com, an online drug reference, ofloxacin belongs to a class of antibiotics called fluoroquinolones. Ofloxacin fights bacterial infections such as bronchitis, pneumonia, chlamydia, gonorrhea, skin infections, urinary tract infections and prostate infections. Mayo Clinic states ofloxacin in a liquid form can be used to treat ear infections.


Drugs.com states patients should not take ofloxacin if they have known allergies to fluoroquinolones such as Cipro, Levaquin and Maxaquin. Notify a health care provider of any heart rhythm problems, allergies to antibiotics, myasthenia gravis, joint disorders, kidney or liver problems, seizure disorders, diabetes, low blood potassium and family history of heart conditions.

Proper Use

Drugs.com states ofloxacin may be taken with or without food at the same time daily. Take ofloxacin with a full glass of water and drink several glasses of water a day to prevent the formation of crystals in the urine. Continue taking this medication until the prescribed dose is gone, even if you feel better. Drugs.com states not to take other medications within two hours of taking ofloxacin. Avoid antacids, ulcer medications, and vitamin and mineral supplements while taking ofloxacin. Other medications, prescribed and over the counter, can decrease the effectiveness of ofloxacin. Mayo Clinic suggests warming ofloxacin ear solution between the hands one to two minutes prior to putting drops in the ear, as cold solution in the ear can cause dizziness.


According to Drugs.com, the effect of taking ofloxacin during pregnancy is not known. Ofloxacin passes through breast milk and can be harmful to a nursing baby. Stop taking ofloxacin if pain, tenderness, swelling or stiffness of joints occurs. Fluoroquinolones such as ofloxacin can cause swelling and rupture of tendons, especially in the heel. Drugs.com states these problems are more common in patients older than 60 years of age.

Side Effects

Drugs.com encourages patients to receive immediate medical help if any of the following life-threatening side effects occur: hives; problems breathing; or swelling of the lips, throat, face or tongue.

Stop using ofloxacin and call a health care provider if these symptoms are experienced: watery or bloody diarrhea, seizures, confusion, dizziness, fainting, fast heart rate, pain and swelling in joints, bruising or bleeding, decreased urine output, numbness in hands or feet, dark-colored urine, fever, headache, blistering or peeling of skin, and red rash.

Less serious side effects include the following: nausea, vomiting, constipation, restlessness, headache or dizziness, muscle pain, problems sleeping, vaginal itching, or discharge and mild skin irritation.


According to the U.S. Food and Drug Administration (FDA), ofloxacin is available orally, as an injection or by otic (ear) solution.

Federal Approval

Ofloxacin has been approved by the FDA for the treatment of bacterial infections.

About this Author

Terri Peerenboom, R.N., began writing for Demand Studios in 2010. She specializes in health-related topics, and has written and published over 100 articles for LIVESTRONG.COM. She holds a Bachelor of Science in nursing from the University of Texas and a Master of Arts in counseling from Sam Houston State University.